廣州醫(yī)科大學(xué)導(dǎo)師：高聰 正文

[導(dǎo)師姓名]
高聰

[所屬院校]
廣州醫(yī)科大學(xué)

[基本信息]
導(dǎo)師姓名：高聰
性別：女
人氣指數(shù)：752
所屬院校：廣州醫(yī)科大學(xué)
所屬院系：
職稱：教授
導(dǎo)師類型：碩導(dǎo)
招生專業(yè)：神經(jīng)病學(xué)

[通訊方式]


[個(gè)人簡述]
高聰，女， 1958年8月出生，籍貫河北，民盟盟員，學(xué)歷本科，醫(yī)學(xué)學(xué)士學(xué)位，廣州醫(yī)科大學(xué)神經(jīng)病學(xué)教研室教授，博士研究生導(dǎo)師，中國免疫學(xué)會(huì)神經(jīng)免疫分會(huì)全國委員，廣東省醫(yī)學(xué)會(huì)神經(jīng)病學(xué)分會(huì)免疫學(xué)組副組長。曾獲得廣東省“南粵優(yōu)秀教師”廣州市優(yōu)秀教師等稱號(hào)。工作業(yè)績近十余年來，從事多發(fā)性硬化、視神經(jīng)脊髓炎的臨床與實(shí)驗(yàn)系列研究，共承擔(dān)、參與了省市級(jí)多個(gè)有關(guān)多發(fā)性硬化的科研課題，在SCI、國家級(jí)核心期刊發(fā)表相關(guān)論文20多篇。近年來，AQP4抗體、納米材料、miRNA成為研究關(guān)注的焦點(diǎn)，課題組在與時(shí)俱進(jìn)，建立了AQP4抗體檢測(cè)、納米材料介導(dǎo)的基因表達(dá)和基因沉默技術(shù)平臺(tái)，試圖為視神經(jīng)脊髓炎的診斷、分型、轉(zhuǎn)歸及預(yù)后判斷尋找新的分子標(biāo)志物，為視神經(jīng)脊髓炎的生物治療提供新的有效手段。此外，一直從事青年卒中的臨床研究，在國際期刊中發(fā)表了近10篇有關(guān)于青年卒中的研究論文，為我國青年卒中的臨床特點(diǎn)提供了重要的資料。培養(yǎng)條件本課題組培養(yǎng)研究生的重點(diǎn)培養(yǎng)內(nèi)容是：基本功必須扎實(shí)、協(xié)作精神必須強(qiáng)、培養(yǎng)科學(xué)研究興趣；研究內(nèi)容一方面在理論上沖擊國際前沿科學(xué)，另一方面要注意與臨床相結(jié)合，重點(diǎn)在于診斷標(biāo)志物和預(yù)后指標(biāo)的研究，神經(jīng)影像學(xué)的改變亦為課題組的研究方向。歡迎有志者加盟我們的團(tuán)隊(duì)。

[科研工作]
近期論文（第一作者或通訊作者）
1.???????? Long Y, Zheng Y, Chen M, Zhang B, Gao C, Shan F, Yang N, Fan Y. Serum thyroid-stimulating hormone and anti-thyroglobulin antibody are independently associated with lesions in spinal cord in central nervous system demyelinating diseases.PLoS One. 2014 Aug 59(8):e1006722.???????? Yang N, Zhang B, Xie L, Yin J, He Y, Yang X, Gao C.The association baseline NIH Stroke Scale score with ABO blood-subtypes in young patients with acute ischemic stroke.Atherosclerosis. 2014 Jul 11236(1):144-149.3.???????? Long Y, Zheng Y, Shan F, Chen M, Fan Y, Zhang B, Gao C, Gao Q, Yang N.Development of a cell-based assay for the detection of anti-aquaporin 1 antibodies in neuromyelitis optica spectrum disorders.J Neuroimmunol. 2014 Aug 15273(1-2):103-104.???????? Zhang B, Yang N, Gao C.Is plasma C3 and C4 levels useful in young cerebral ischemic stroke patients? Associations with prognosis at 3 months.J Thromb Thrombolysis. 2014 Jun 18. [Epub ahead of print]5.???????? Long Y, Gao C.Brain embolism secondary to cardiac myxoma in fifteen Chinese patients.ScientificWorldJournal. 2014 Mar 92014:7182466.???????? Long Y, Zheng Y, Chen M, Zhang B, Gao C, Gao Q, Yin JR, Pu S, Xie C.Antineutrophil cytoplasmic antibodies in patients with idiopathic inflammatory-demyelinating diseases.Neuroimmunomodulation. 201421(6):297-303. 7.???????? Long Y, Chen M, Zhang B, Gao C, Zheng Y, Xie L, Gao Q, Yin J. Brain gadolinium enhancement along the ventricular and leptomeningeal regions in patients with aquaporin-4 antibodies in cerebral spinal fluid. J Neuroimmunol. 2014 Apr 15269(1-2):62-7.8.???????? long Y, He Y, Zheng Y, Chen M, Zhang B, Gao C. Serum anticardiolipin antibodies in patients with neuromyelitis optica spectrum disorder.J Neurol. 2013 Dec260(12):3150-7.9.???????? Gao C, Huang L, Long Y, Zheng J, Yang J, Pu S, Xie L.Y-39983, a selective Rho-kinase inhibitor, attenuates experimental autoimmune encephalomyelitis via inhibition of demyelination.Neuroimmunomodulation. 201320(6):334-40. 10.???? Yang N, Zhang B, Gao C.The baseline NIHSS score in female and male patients and short-time outcome: a study in young ischemic stroke.J Thromb Thrombolysis. 2014 May37(4):565-70.11.???? Long Y, Gao C, Qiu W, Hu X, Peng F, Lu Z.Antibodies target microvessels in neuromyelitis optica and multiple sclerosis patients. Neurol Res. 2013 Nov35(9):922-9.12.???? Liang B, Deng JJ, Yuan F, Yang N, Li W, Yin JR, Pu SX, Xie LC, Gao C, Zhang LM.Efficient gene transfection in the neurotypic cells by star-shaped polymer consisting of β-cyclodextrin core and poly(amidoamine) dendron arms.Carbohydr Polym. 2013 Apr 1594(1):185-92.13.???? Zhang B, Gao C, Hou Q, Yin J, Xie L, Pu S, Yi Y, Gao Q.The potent different risk factors for cerebral infarction in young patients with and without type 2 diabetes: subanalysis of the Young Cerebral Infarction Study (YCIS).Atherosclerosis. 2012 Mar221(1):215-20. 14.???? Zhang B, Gao C, Hou Q, Yin J, Xie L, Pu S, Yi Y, Gao Q.Different independent susceptibility markers for first-ever cerebral infarction and myocardial infarction in young patients.J Neurol. 2012 Jul259(7):1420-5. 15.???? Zhang B, Zhang W, Li X, Pu S, Yin J, Yang N, Yi Y, Gao Q, Gao C.Admission markers predict lacunar and non-lacunar stroke in young patients.Thromb Res. 2011 Jul128(1):14-7. 16.???? Zhang B, Pu S, Zhang W, Yang N, Shen G, Yin J, Yi Y, Gao Q, Gao C.Sex differences in risk factors, etiology, and short-term outcome of cerebral infarction in young patients.Atherosclerosis. 2011 Jun216(2):420-5. 17.???? Zhang B, Gao C, Yang N, Zhang W, Song X, Yin J, Pu S, Yi Y, Gao Q.Is elevated SUA associated with a worse outcome in young Chinese patients with acute cerebral ischemic stroke?BMC Neurol. 2010 Sep 1810:82.18.???? Gao C, Zhang B, Zhang W, Pu S, Yin J, Gao Q.Serum prealbumin (transthyretin) predict good outcome in young patients with cerebral infarction.Clin Exp Med. 2011 Mar11(1):49-54. 19.???? Zhang B, Song X, Liang B, Hou Q, Pu S, Ying JR, Gao C.The clinical study of POEMS syndrome in China.Neuro Endocrinol Lett. 201031(2):229-37.20.???? Zhang B, Pu S, Li B, Ying J, Song XW, Gao C.Comparison of serum apolipoprotein A-I between Chinese multiple sclerosis and other related autoimmune disease.Lipids Health Dis. 2010 Mar 299:34.

[教育背景]
學(xué)習(xí)經(jīng)歷:1982年畢業(yè)于中山醫(yī)科大學(xué)（現(xiàn)中山大學(xué)），獲學(xué)士學(xué)位，畢業(yè)后一直在廣州醫(yī)科大學(xué)附屬醫(yī)院工作，從事神經(jīng)病學(xué)專業(yè)的臨床、教學(xué)和科研工作。

廣州醫(yī)科大學(xué)

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