寧波大學醫(yī)學院導師:肖丙秀

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寧波大學醫(yī)學院導師:肖丙秀

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寧波大學醫(yī)學院導師:肖丙秀 正文

[導師姓名]
肖丙秀

[所屬院校]
寧波大學

[基本信息]
導師姓名:肖丙秀
性別:女
人氣指數(shù):1731
所屬院校:寧波大學
所屬院系:醫(yī)學院
職稱:高級實驗師
導師類型:
招生專業(yè):生物化學與分子生物學
研究領域:腫瘤分子生物學



[通訊方式]
辦公電話:0574-87609605
電子郵件:xiaobingxiu@nbu.edu.cn
通訊地址:浙江省寧波市風華路818號寧波大學醫(yī)學院

[個人簡述]
肖丙秀,女,學士,副高職稱。曾在美國明尼蘇達大學Hormel研究所癌生物學實驗室進修學習。目前從事腫瘤學、分子生物學教學與研究工作。曾參與完成國家自然科學基金課題3項。主持完成浙江省自然科學基金項目和浙江省科技廳科研項目各1 項,在腫瘤相關非編碼rna研究方面具有較豐富的經驗,形成了胃癌診治研究特色。近年來發(fā)表論文30多篇,其中SCI收錄20多篇。獲得省科技獎三等獎2項、市廳級科技獎一等獎2項、市廳級科技獎二等獎2項、市廳級科技獎三等獎2項和市廳級科技獎三等獎2項等,其中“外周血中微量消化系統(tǒng)惡性腫瘤細胞的分析及其臨床應用”已在4家醫(yī)院(包括2家三甲醫(yī)院)推廣應用,取得了良好的社會效益,成果獲得2006年浙江省科學技術獎三等獎和浙江省醫(yī)藥衛(wèi)生科技創(chuàng)新獎一等獎。申報發(fā)表專利6項,其中2項已授權。

[科研工作]
1: Shao Y, Li J, Lu R, Li T, Yang Y, Xiao B, Guo J. Global circular RNAexpression profile of human gastric cancer and its clinical significance. Cancer Med. 2017 Jun6(6):1173-1180. doi: 10.1002/cam4.1055. Epub 2017 May 23. PubMedPMID: 28544609 PubMed Central PMCID: PMC5463069.2: Fu L, Wu S, Yao T, Chen Q, Xie Y, Ying S, Chen Z, Xiao B, Hu Y. Decreasedexpression of hsa_circ_0003570 in hepatocellular carcinoma and its clinicalsignificance. J Clin Lab Anal. 2017 May 11. doi: 10.1002/jcla.22239. [Epub ahead of print] PubMed PMID: 28493512.3: Chen S, Li T, Zhao Q, Xiao B, Guo J. Using circular RNA hsa_circ_0000190 as a new biomarker in the diagnosis of gastric cancer. Clin Chim Acta. 2017Mar466:167-171. doi: 10.1016/j.cca.2017.01.025. Epub 2017 Jan 24. PubMed PMID:28130019.4: Li P, Chen H, Chen S, Mo X, Li T, Xiao B, Yu R, Guo J. Circular RNA 0000096affects cell growth and migration in gastric cancer. Br J Cancer. 2017 Feb28116(5):626-633. doi: 10.1038/bjc.2016.451. Epub 2017 Jan 12. PubMed PMID:28081541 PubMed Central PMCID: PMC5344286.5: Liu GY, Xiao BP, Luo CF, Zhuang YQ, Xu RM, Ma WH. Results of a modifiedposterolateral approach for the isolated posterolateral tibial plateau fracture. Indian J Orthop. 2016 Mar-Apr50(2):117-22. doi: 10.4103/0019-5413.177578. PubMedPMID: 27053799 PubMed Central PMCID: PMC4800952.6: Li P, Chen S, Chen H, Mo X, Li T, Shao Y, Xiao B, Guo J. Using circular RNA asa novel type of biomarker in the screening of gastric cancer. Clin Chim Acta.2015 Apr 15444:132-6. doi: 10.1016/j.cca.2015.02.018. Epub 2015 Feb 14. PubMedPMID: 25689795.7: Xia T, Liao Q, Jiang X, Shao Y, Xiao B, Xi Y, Guo J. Long noncoding RNAassociated-competing endogenous RNAs in gastric cancer. Sci Rep. 2014 Aug154:6088. doi: 10.1038/srep06088. PubMed PMID: 25124853 PubMed Central PMCID:PMC4133709.8: Shao Y, Ye M, Jiang X, Sun W, Ding X, Liu Z, Ye G, Zhang X, Xiao B, Guo J.Gastric juice long noncoding RNA used as a tumor marker for screening gastriccancer. Cancer. 2014 Nov 1120(21):3320-8. doi: 10.1002/cncr.28882. Epub 2014 Jul1. PubMed PMID: 24986041.9: Yu X, Wu Y, Liu Y, Deng H, Shen Z, Xiao B, Guo J. miR-21, miR-106b and miR-375as novel potential biomarkers for laryngeal squamous cell carcinoma. Curr PharmBiotechnol. 201415(5):503-8. PubMed PMID: 24846066.10: Li PF, Chen SC, Xia T, Jiang XM, Shao YF, Xiao BX, Guo JM. Non-coding RNAsand gastric cancer. World J Gastroenterol. 2014 May 1420(18):5411-9. doi:10.3748/wjg.v20.i18.5411. Review. PubMed PMID: 24833871 PubMed Central PMCID:PMC4017056.11: Yu X, Song H, Xia T, Han S, Xiao B, Luo L, Xi Y, Guo J. Growth inhibitoryeffects of three miR-129 family members on gastric cancer. Gene. 2013 Dec10532(1):87-93. doi: 10.1016/j.gene.2013.09.048. Epub 2013 Sep 20. PubMed PMID: 24055727.12: Xiao B, Guo J. Long noncoding RNA AC096655.1-002 has been officially named asgastric cancer-associated transcript 1, GACAT1. Tumour Biol. 2013 Oct34(5):3271.doi: 10.1007/s13277-013-0916-7. Epub 2013 Jun 12. PubMed PMID: 23754450.13: Cui L, Zhang X, Ye G, Zheng T, Song H, Deng H, Xiao B, Xia T, Yu X, Le Y, GuoJ. Gastric juice MicroRNAs as potential biomarkers for the screening of gastriccancer. Cancer. 2013 May 1119(9):1618-26. doi: 10.1002/cncr.27903. Epub 2013 Jan18. PubMed PMID: 23335180.14: Deng H, Guo Y, Song H, Xiao B, Sun W, Liu Z, Yu X, Xia T, Cui L, Guo J.MicroRNA-195 and microRNA-378 mediate tumor growth suppression by epigeneticalregulation in gastric cancer. Gene. 2013 Apr 15518(2):351-9. doi:10.1016/j.gene.2012.12.103. Epub 2013 Jan 17. PubMed PMID: 23333942.15: Zhou H, Xiao B, Zhou F, Deng H, Zhang X, Lou Y, Gong Z, Du C, Guo J. MiR-421 is a functional marker of circulating tumor cells in gastric cancer patients.Biomarkers. 2012 Mar17(2):104-10. doi: 10.3109/1354750X.2011.614961. Epub 2012Jan 23. PubMed PMID: 22263628.16: Li LZ, Deng HX, Lou WZ, Sun XY, Song MW, Tao J, Xiao BX, Guo JM. Growthinhibitory effect of 4-phenyl butyric acid on human gastric cancer cells isassociated with cell cycle arrest. World J Gastroenterol. 2012 Jan 718(1):79-83.doi: 10.3748/wjg.v18.i1.79. PubMed PMID: 22228974 PubMed Central PMCID:PMC3251809.17: Cheng J, Deng H, Xiao B, Zhou H, Zhou F, Shen Z, Guo J. piR-823, a novelnon-coding small RNA, demonstrates in vitro and in vivo tumor suppressiveactivity in human gastric cancer cells. Cancer Lett. 2012 Feb 1315(1):12-7. doi:10.1016/j.canlet.2011.10.004. Epub 2011 Oct 10. PubMed PMID: 22047710.18: Cui L, Lou Y, Zhang X, Zhou H, Deng H, Song H, Yu X, Xiao B, Wang W, Guo J.Detection of circulating tumor cells in peripheral blood from patients withgastric cancer using piRNAs as markers. Clin Biochem. 2011 Sep44(13):1050-7.doi: 10.1016/j.clinbiochem.2011.06.004. Epub 2011 Jun 17. PubMed PMID: 21704610.
序號項目名稱計劃起始日期計劃完成日期項目編號項目來源1新型標志物lncRNA在胃癌輔助診斷中的臨床價值分析2014-06-012016-06-302014C33222省科技廳/公益技術應用研究2長鏈非編碼RNA影響胃癌細胞生長的機制研究2013-01-012014-12-31CBSKL201306國家重點實驗室/開放基金3長鏈非編碼RNA影響胃癌發(fā)生的機制研究2012-02-012013-12-312012A610207市科技局/自然科學基金4胃癌相關長鏈非編碼RNA的鑒定2011-12-012013-11-01XKL11D2127學科項目/市級重點5實時定量檢測外周血中腫瘤相關非編碼RNA的方法研究2008-01-012009-12-012008F70052省科技廳/其他6胃癌相關微小RNA的功能分析2008-01-012010-12-01Y207244省自然科學基金/一般項目

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