寧波大學醫(yī)學院導(dǎo)師:牧啟田
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寧波大學醫(yī)學院導(dǎo)師:牧啟田 正文
[導(dǎo)師姓名]牧啟田
[所屬院校]
寧波大學
[基本信息]
導(dǎo)師姓名:牧啟田
性別:男
人氣指數(shù):3538
所屬院校:寧波大學
所屬院系:醫(yī)學院
職稱:主任技師
導(dǎo)師類型:
招生專業(yè):臨床檢驗診斷學
研究領(lǐng)域:血液分子遺傳學
[通訊方式]
辦公電話:0574-87085084
電子郵件:muqitian@163.com
[個人簡述]
牧啟田,主任技師,九三學社社員,干細胞移植實驗室副主任,寧波市領(lǐng)軍拔尖人才培養(yǎng)工程第二層次培養(yǎng)對象,寧波市醫(yī)學會血液分會委員,寧波市寧波大學碩士生導(dǎo)師,tumor biology 雜志審稿人。1996年獲皖南醫(yī)學院臨床醫(yī)學學士學位,2003年獲暨南大學血液內(nèi)科學碩士學位,2013.3獲得浙江大學博士學位。2003年至今一直在寧波市第一醫(yī)院寧波市干細胞移植重點實驗室工作,從事白血病分子細胞遺傳學研究。發(fā)表論文60余篇, 其中sci論文10余篇,2011年美國ASH Meeting 論文摘要交流1篇,2012年美國ASH Meeting 論以poster形式論文交流1篇,多次全國學術(shù)會議做論文口頭報告。目前,主持浙江省自然科學基金項目1項,市級科技項目1項;參與獲得市廳級科技創(chuàng)新進步獎5項,獲得2007-2008年度寧波市自然科學論文優(yōu)秀獎1項。
[科研工作]
代表性的文章:
1. Chen J, Mu Q, Li X, Yin X, Yu M, Jin J, Li C, Zhou Y, Zhou J, Suo S, Lu D, Jin J. Homoharringtonine targets Smad3 and TGF-β pathway to inhibit the proliferation of acute myeloid leukemia cells. Oncotarget, 2017 Jun 208(25):40318-40326.(并列第一作者).
2. Mu Q, Guo L, Hu Y, Sheng L, Zhang Y, Wu N, Chen Y, Shi C, Shi S, Wu Y, Ouyang G. SNX2-ABL1-positive acute lymphoblastic leukemia possibly has a poor prognosis. Leuk Lymphoma. 2017, Sep58(9):1-3.
3. Qitian Mu,Ying Chen,Huiling Zhu,Yi Zhang,Ningning Wu,Yanru Lou,Songqiu Shi,Ying Wu,Cong Shi,Guifang Ouyang. Isolated trisomy 13 inrefractory anemia with excess blasts: report of two cases and a brief literature review of this possible association,LeukLymphoma, 2016, 57(2):493-495.
4. Shasha Lu, Qitian Mu,Mengxia Yu,Xiufeng Yin,Jian Chen,Jie Jin.Overexpression of musashi2 is possibly associated with chemoresistance in T-cell acute lymphoblastic leukemia,Leuk Lymphoma, 2016, 57(2):467-469。
5. Ma QL, Wang JH, Wang YG, Hu C, Mu QT, Yu MX, Wang L, Wang DM, Yang M, Yin XF, Chen FF, Lu SS, et al. High IDH1 expression is associated with a poor prognosis in cytogenetically normal acute myeloid leukemia. Int J Cancer 2015137:1058-1065。
6. Mu Q, Ma Q, Lu S, Zhang T, Yu M, Huang X, Chen J, Jin J. 10058-F4, a c-Myc inhibitor, markedly increases valproic acid-induced cell death in Jurkat and CCRF-CEM T-lymphoblastic leukemia cells. Oncol Lett 20148: 1355-9.
7. Yin XF, Ma QL, Mu QT, Shao L, Wang SS, Meng HT, Xu WL, Wang YG, Chen ZM, Chen FF, Jin J. Outcome prediction by the transcript level of BCR-ABL at 3 months in patients with chronic myeloid leukemia treated with imatinib--a single institution historical experience. Leuk Res 201438: 1191-8.
8. Lu S, Xu Y, Mu Q, Cao L, Chen J, Zhu Z, Lou Y, Meng H, Qian W, Tong H, Mai W, Huang J, et al. The risk of hepatitis B virus reactivation and the role of antiviral prophylaxis in hepatitis B surface antigen negative/hepatitis B core antibody positive patients with diffuse large B-cell lymphoma receiving rituximab-based chemotherapy. Leuk Lymphoma 2014: 1-6.
9. Mu Q, Wang Y, Chen B, Qian W, Meng H, Tong H, Chen F, Ma Q, Ni W, Chen S, Jin J. High expression of Musashi-2 indicates poor prognosis in adult B-cell acute lymphoblastic leukemia. Leuk Res 201337: 922-7.
10. Mu Q, Ma Q, Wang Y, Chen Z, Tong X, Chen FF, Lu Y, Jin J. Cytogenetic profile of 1,863 Ph/BCR-ABL-positive chronic myelogenous leukemia patients from the Chinese population. Ann Hematol 201291: 1065-72.
11. Yang L, Ruan LM, Ye HH, Cui HB, Mu QT, Lou YR, Ji YX, Li WZ, Sun DH, Chen XB. Depression is associated with lower circulating endothelial progenitor cells and increased inflammatory markers. Acta Neuropsychiatr 201123: 235-40.
12. Mu Q, Cheng Y, Xu W, Wang Y, Chen Z, Jin J. Acquired Robertsonian translocation is not always suggestive of poor prognosis: a case of acquired Rob(1314) in Philadelphia chromosome-negative cells of chronic myelogenous leukemia. Leuk Lymphoma 201051: 2141-3.
13. Zhuo Z, Zhang L, Mu Q, Lou Y, Gong Z, Shi Y, Ouyang G, Zhang Y. The effect of combination treatment with docosahexaenoic acid and 5-fluorouracil on the mRNA expression of apoptosis-related genes, including the novel gene BCL2L12, in gastric cancer cells. In Vitro Cell Dev Biol Anim 200945: 69-74.
1.《Bcl2l12基因在白血病中表達及其臨床意義》,寧波市醫(yī)學科技計劃項目基金。
2.《Musashi-2基因在急性淋巴細胞白血病中表達的臨床意義研究》,寧波市醫(yī)學科技計劃項目基金。
3.《Musashi-2基因在B細胞急性淋巴細胞白血病中分子作用機制研究》, 寧波市自然科學基金項目。
4.《MSI2通過p53-WNT通路促進成人B細胞急性淋巴細胞白血病生長作用的機制研究》,浙江省自然科學基金項目。
[教育背景]
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