蘭州大學(xué)研究生導(dǎo)師：陳強(qiáng) 正文

　　學(xué)習(xí)經(jīng)歷

　　1997－2001 蘭州大學(xué)生命科學(xué)學(xué)院生物化學(xué)專業(yè) 博士

　　1995－1996 意大利國家野生動(dòng)物研究所（Istituto Nazionale per la Funa Selvatica）訪問學(xué)者

　　1987－1990 蘭州大學(xué)生物系動(dòng)物學(xué)專業(yè) 碩士

　　1979－1983 蘭州大學(xué)生物系動(dòng)物學(xué)專業(yè) 學(xué)士

　　工作經(jīng)歷

　　2004-     蘭州大學(xué)生命科學(xué)學(xué)院 教授

　　2004-2010 蘭州大學(xué)生命科學(xué)學(xué)院副院長

　　2006－    蘭州大學(xué)生物學(xué)實(shí)驗(yàn)教學(xué)中心（國家級實(shí)驗(yàn)教學(xué)示范中心）主任

　　1997-2004 蘭州大學(xué)生命科學(xué)學(xué)院 副教授

　　1990-1997 蘭州大學(xué)生物系 講師

　　1983-1990 蘭州大學(xué)生物系 助教

　　教學(xué)及指導(dǎo)研究生情況

　　在讀博士研究生3名，碩士研究生9名。已畢業(yè)博士研究生5名，碩士研究45名。

　　發(fā)表論文及專著

　　2015

　　59. Zhang, Yang, Shiwei Liang, Jianzheng He, Yucheng Bai, Yonggang Niu, Xiaolong Tang, Dongqin Li and Qiang Chen. "Oxidative Stress and Antioxidant Status in a Lizard Phrynocephalus Vlangalii at Different Altitudes or Acclimated to Hypoxia." Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 190,  (2015): 9-14.

　　58. Yang, Yongzhi, Lizhong Wang, Jin Han, Xiaolong Tang, Ming Ma, Kun Wang, Xiao Zhang, Qian Ren, Qiang Chen and Qiang Qiu. "Comparative Transcriptomic Analysis Revealed Adaptation Mechanism of Phrynocephalus Erythrurus, the Highest Altitude Lizard Living in the Qinghai-Tibet Plateau." BMC evolutionary biology 15, no. 1 (2015): 101.

　　57. Xin, Ying, Xiaolong Tang, Huihui Wang, Songsong Lu, Yan Wang, Yang Zhang and Qiang Chen. "Functional Characterization and Expression Analysis of Myoglobin in High-Altitude Lizard Phrynocephalus Erythrurus." Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 188,  (2015): 31-36.

　　56. Wang, Cui, Xiaolong Tang, Ying Xin, Feng Yue, Xuefeng Yan, Bingbing Liu, Bei An, Xi Wang and Qiang Chen. "Identification of Sex Chromosomes by Means of Comparative Genomic Hybridization in a Lizard, Eremias Multiocellata." Zoological science 32, no. 2 (2015): 151-156.

　　55. Lu, Songsong, Ying Xin, Xiaolong Tang, Feng Yue, Huihui Wang, Yucheng Bai, Yonggang Niu and Qiang Chen. "Differences in Hematological Traits between High-and Low-Altitude Lizards (Genus Phrynocephalus)." PloS one 10, no. 5 (2015).

　　2014

　　54. Yuan Fang, Shuo Li , Huabin Zhou, Xiaozhu Tian, Shuangyu Lv, Qiang Chen? Opiorphin increases blood pressure of conscious rats through renin-angiotensin system (RAS). Peptides 55 (2014) 47-51

　　53. XIN, Ying, Huihui WANG, Xiaolong Tang, Songsong LU, Weixin LI, Yang ZHANG, Shiwei LIANG and Qiang CHEN. "Characterisation and Expression Analysis of Sox9 in the Multiocellated Racerunner, Eremias Multiocellata." Asian Herpetological Research 2,  (2014): 004.

　　2013

　　52. Xiaolong Tang, Ying Xin, Huihui Wang, Weixin Li, Yang Zhang, Shiwei Liang, Jianzheng He, Ningbo Wang, Ming Ma and Qiang Chen*. "Metabolic Characteristics and Response to High Altitude in Phrynocephalus Erythrurus (Lacertilia: Agamidae), a Lizard Dwell at Altitudes Higher Than Any Other Living Lizards in the World." PLoS One,  (2013).

　　51. Xiaolong Tang, F. Yue, J. Z. He, N. B. Wang, M. Ma, J. R. Mo and Q. Chen. "Ontogenetic and Sexual Differences of Thermal Biology and Locomotor Performance in a Lacertid Lizard, Eremias Multiocellata." Zoology (Jena) 116, no. 6 (2013): 331-5.

　　50. He, J., M. Xiu, Xiaolong Tang, F. Yue, N. Wang, S. Yang and Q. Chen. "The Different Mechanisms of Hypoxic Acclimatization and Adaptation in Lizard Phrynocephalus Vlangalii Living on Qinghai-Tibet Plateau." J Exp Zool A Ecol Genet Physiol 319, no. 3 (2013): 117-23.

　　49. He, J., M. Xiu, Xiaolong Tang, N. Wang, Y. Xin, W. Li and Q. Chen. "Thermoregulatory and Metabolic Responses to Hypoxia in the Oviparous Lizard, Phrynocephalus Przewalskii." Comp Biochem Physiol A Mol Integr Physiol 165, no. 2 (2013): 207-13.

　　48. Yang, S., Yang, A., Shao, T., Su, S., Chen, Q.* (2013) Synergistic analgesic effects between neuronostatin and morphine at thesupraspinal level. Peptides 44: 105– 110

　　47. Lv, S., Yang, Y., Chen, Q.* (2013) Regulation of feeding behavior, gastrointestinal function and fluid homeostasisby apelin. Peptides 44: 87– 92

　　46. Mo, J., Yang, A., Chen, Z., Shao, T., Zhang, Y., & Chen, Q. (2013). Neuronostatin ameliorates sodium taurocholate-induced acute pancreatitis in rats. Digestive diseases and sciences, 58(10), 2903-2907.

　　2012

　　45. Tang, X., Yue, F., Ma, M., Wang, N., He, J., Chen, Q.* (2012) Effects of Thermal and Hydric Conditions on Egg Incubation and Hatchling Phenotypes in Two Phrynocephalus Lizards. Asian Herpetological Research 3(3): 184-191

　　44. Tang, X., Yue, F., Zhang, D., Yan, X., Xin, Y., Wang, C., Chen, Q.* (2012) The effect of operational sex ratio on sex allocation and neonate phenotype in a viviparous lizard Eremias multiocellata Amphibia-Reptilia 33: 485-493

　　43. Su, S., Yang, A., Yang, S., Wang, N., Lu, S., Wang, H., Chen, Q.*　(2012) Intracerebroventricular administration of neuronostatin delays gastric emptying　and gastrointestinal transit in mice.　Peptides 35: 31–35

　　42. Lv, S., Qin, Y., Wang, H., Xu, N., Yang, Y., Chen, Q.* (2012) Centrally administered apelin-13 induces depression-like behavior in mice. Brain Res Bull 88(6):574-80.

　　41. Tang, X., Yue, F., Yan, X., Zhang, D., Xin, Y., Wang, C., Chen, Q.* (2012) Effects of gestation temperature on offspring sex and maternal reproduction in aviviparous lizard (Eremias multiocellata) living at high altitude. Journal of Thermal Biology 37: 438–444

　　40. Yang, S., Yang, A., Su, S., Wang, H., Wang, N., Chen, Q.* (2012) Neuronostatin induces hyperalgesia in formalin test in mice. Neuroscience Letters 506: 126–130

　　39. Lv, S., Yang, Y., Qin, Y., Mo, J., Wang, N., Wang, Y., Chen, Q.* (2012) Central apelin-13 inhibits food intake via the CRF receptor in mice. Peptides 33: 132-138

　　38. Yue, F., Tang, X., Zhang, D., Yan, X., Xin, Y., Chen, Q.* (2012) Body temperature and standard metabolic rate of female viviparous lizard Eremias multiocellata during reproduction. Canadian Journal of Zoology 90: 79–84

　　37. Xin, Y., Tang, X., Yue, F., Zhang, D., Yan, X., Wang, C., Chen, Q.* (2012) Isolation and Sequence Analysis of Sox Genes from lizard Eremias multiocellata. Russian Journal of Genetics 48(1): 88-94

　　2011

　　36. Yang, A., Ji, Y., Su, S., Yang, S., Lu, S., Mi, Z., Yang, Q., Chen, Q.* (2011) Intracerebroventricular administration of neuronostatin induces depression-like effect in forced swim test of mice. Peptides 32: 1948–1952

　　35. Yang, A., Ge, W., Lu, S., Yang, S., Su, S., Mi, Z., Chen, Q.* (2011) Central administration of neuronostatin induces antinociception in mice. Peptides 32: 1893–1901

　　34. Yan, X., Tang, X., Yue, F., Zhang, D., Xin, Y., Wang, C., Chen, Q.* (2011) Influence of ambient temperature on maternal thermoregulation and neonate phenotypes in a viviparous lizard, Eremias multiocellata, during the gestation period. Journal of Thermal Biology 36: 187–192

　　33. 呂雙瑜 楊愛民 修明慧 楊艷杰 陳強(qiáng)*  (2011) 側(cè)腦室注射脂肪酸合成酶抑制劑C75對小鼠學(xué)習(xí)記憶的影響，中華行為醫(yī)學(xué)與腦科學(xué)雜志 20（1）：51-52

　　32. Lv, S., Yang, Y., Qin, Y., Xiong, X., Chen, Q.* (2011) Effect of centrally administered apelin-13 on gastric emptying and gastrointestinal transit in mice. Peptides 32: 978–982

　　31. Yang, Q., Lu, S., Tian, X., Yang, A., Ge, W., Chen, Q.* (2011) The antidepressant-like effect of human opiorphin via opioid-dependent pathways in mice. Neuroscience Letters 489: 131-135

　　1993-2010

　　30. Yang, Y., Lv, S., Xiu, M., Xu, N., Chen, Q.* (2010) Intracerebroventricular administration of apelin-13 inhibits distal colonic transit in mice. Peptides 31: 2241–2246

　　29. Zhang, D., Yue, F., Tang, X., Chen, Z., Li, R., Chen, Q.* (2010) Effect of gestation temperature on sexual and morphological phenotypes of offsprings in a viviparous lizard, Eremias multiocellata. Journal of Thermal Biology 35: 129–133

　　28. Tian, X., Chen, J., Xiong, W., He, T., Chen, Q.* (2009) Effects and underlying mechanisms of human opiorphin on colonic motility and nociception in mice. Peptides 30:1348-54

　　27. Xu, N., Wang, H., Fan, L., Chen, Q.* (2009) Supraspinal administration of apelin-13 induces antinociception via the opioid receptor in mice. Peptides 30: 1153–1157

　　26. Li, L., Lu, Y., Xiong, W., Liu, J., Chen, Q.* (2008) Effect of centrally administered C75, a fatty acid synthase inhibitor, on gastric emptying and gastrointestinal transit in mice. European Journal of Pharmacology 595: 90–94

　　25. Chen, J., Long, Y., Han, H., Wang, T., Chen, Q.,* Wang, R.* (2008) Water-solutable derivates of propolis mitigates scopolamine-induced learning and memory impairment in mice. Pharmacology, Biochemistry and Behavior 90:441-446

　　24. Zai, K., Hu, L., Chen, J., Fu, C., Chen, Q.* (2008) Chrysin induced hyperalgesia via GABAA receptor in mice. Planta Medica 74:1229-1234

　　23. 歐陽建梅 隴源 房克難 王銳 陳強(qiáng)*, (2007) 蜂膠乙醇提取物(EEP)對豚鼠胸主動(dòng)脈的舒張作用, 現(xiàn)代生物醫(yī)學(xué)進(jìn)展 (9):1286-1289

　　22. Zhao, Q., Chen, Q., Feng, Y., Lin,X., Wang, R.* (2005) [TIC4] endomorphins, analogues of endomorphins, have significantly　nhanced vasorelaxant effects in rat aorta rings. Protein Pept. Lett 12(4), 323-326

　　21. Xu, P., Chen, Q., Li, H., Yu, Y., Yan, X., Wang, R.* (2005) The relaxant effect of dobutamine on porcine coronary arterial ring segments. Pharmazie 60 375-377

　　20. Feng, Y., Zhao, Q., Chen, Q., Wang, R.* (2005) Vasorelaxant responses to endomorphin1[ ], analogues of endomorphins, in rat aorta rings.Yand endomorphine2[ pharmazie 60:851-855

　　19. Fu, C., Kong, Z., Wang, K., Yang, Q., Zhai, K., Chen, Q.,*　Wang, R.*　(2005) Effects and mechanisms of supraspinal administration of rat/mouse　hemokinin-1, a mammalian tachykinin peptide, on nociception in mice. Brain Research 1056, 51-58

　　18. Zhao, Q., Chen, Q., Yang, D., Feng, Y., Long, Y., Wang, P., Wang, R.* (2005) Endomorphin 1[c] and endomorphin 2[c], endomorphins analogues containing a reduced (CH2NH) amide bond between Tyr1 and Pro2, display partial agonist potency but significant antinociception. Life Sci., 77, 1155-1165

　　17. Xu, P., Chang, M., Chen, L., Chen, Q.,* Yan, X.,* Wang, R.* (2004) The relaxant Effect of nociceptin on porcine coronary arterial ring segment. Can. J. Physiol. Pharmacol 82, 993-999

　　16. Lin, X., Chen, Q., Xue, L., Ma, X., Wang, R.* (2004) Endomorphins, endogenous opioid peptides induce apoptosis in human leukemia HL-60 cells. Can. J. Physiol. Pharmacol 82, 1018-1025

　　15. Chen, L., Fang, Q., Chen, Q.,* Guo, J., Wang, Z., Chen, Y., Wang, R. * (2004) Study in vitro and in vivo of nociceptin/orphanin FQ(1–13)NH2 analogues substituting N-Me-Gly for Gly2 or Gly3. Peptides 25, 1349-1354

　　14. Lin, X., Cai, Y., Li, Z., Chen, Q., Wang, R.*(2003) Structure determination, apoptosis induction, and telomerase inhibition of CFP-2, a novel lichenin from Cladonia furcata. Biochim. Biophys. Acta 1622: 99

　　13. Lin, X., Yang, D., Cai, W., Zhao, Q., Gao, Y., Chen, Q., Wang, R.* (2003) Endomorphins, endogenous opioid peptide, provide antioxidant defense in the brain against free radicall-induced damage. Biochim. Biophys. Acta (BBA)-Mol. Basis. Dis 1639: 195

　　12. Chen, Q., Chen, Y., Chen, L., Yang, D., Dong, S., Wang, R.* (2001) The effects of the synthetic nocistation on blood vessel activities. Chin. Sci. Bull 46(8): 275

　　11. 吳寧, 霍笑風(fēng), 陳強(qiáng), 楊頂建, 王 銳* (2001) 側(cè)腦室注射內(nèi)嗎啡肽-1對麻醉大鼠血壓的影響. 藥學(xué)學(xué)報(bào) 36(10): 731"

　　10. 吳寧, 任維華, 霍笑風(fēng), 陳強(qiáng), 王 銳* (2001) 內(nèi)嗎啡肽及其類似物對心血管系統(tǒng)的作用. 藥學(xué)學(xué)報(bào) 36(4): 241

　　9. 陳勇, 陳鯉翔, 陳強(qiáng), 楊頂建, 彭雅麗, 楊祺, 王 銳* (2001) 痛穩(wěn)素碳末端八肽翻轉(zhuǎn)孤啡肽對抗嗎啡鎮(zhèn)痛的作用. 中國藥理學(xué)通報(bào)17(4): 383

　　8. Chen, Q., Chen, L., Chen, Y., Yang, D., Peng, Y., Dong, S., Wang, R.* (2000) Effects of the synthesized nocistatin and nocistatin (10-17) on analgesia induced by endomorphin-1 and endomorphin-2. Acta Pharmacol. Sin 21(11): 1053"

　　7. 陳強(qiáng), 陳勇, 陳鯉翔, 楊頂建, 董守良, 王 銳* (2000) 痛穩(wěn)素的合成及其對血管活性的影響. 科學(xué)通報(bào) 45(24): 2620）

　　6. Chen, Q., Chang, C., Liu, N., E. Randi, V. Licchini, Mitochondrial DNA intro-gression between two parapatric species (Alectoris) in Central China動(dòng)物學(xué)報(bào)1999,45(4):456

　　5. 陳強(qiáng), 李仁德, 劉迺發(fā), (1999) 雄性密點(diǎn)麻蜥精巢支持細(xì)胞和間質(zhì)細(xì)胞的年周期變化. 蘭州大學(xué)學(xué)報(bào) 35(專輯)80-82

　　4. Li, R., Chen, Qiang., Liu, N. (1998) Effects of body temperature on electrocardiograms of lizard Eremias multiocellata. 動(dòng)物學(xué)研究 19(4): 269-276

　　3. 李仁德, 陳強(qiáng), 劉迺發(fā), (1996) 溫度對蜥蜴血紅蛋白及血漿總蛋白濃度的影響, 動(dòng)物學(xué)報(bào), 42(3):247-252

　　2. 陳強(qiáng), (1995) 麗斑麻蜥和草原沙蜥靜止代謝率的研究, 蘭州大學(xué)學(xué)報(bào)(自然科學(xué)版), 31(1):68-71

　　1. 陳強(qiáng), 韓昭雪, (1993) 變色沙蜥繁殖的研究, 蘭州大學(xué)學(xué)報(bào)(自然科學(xué)版) 29(4):199- 204

　　研究方向

　　蜥蜴對干旱、高寒、缺氧等環(huán)境的適應(yīng)機(jī)制

　　肽類激素或其它多肽的生物學(xué)活性與作用機(jī)理

　　項(xiàng)目成果

　　密點(diǎn)麻蜥性別決定機(jī)制的研究  國家自然科學(xué)基金面上項(xiàng)目，2007.1-2009.12，（主持）

　　三種沙蜥的性別決定機(jī)制以及孵化溫度對其幼體生存能力影響的研究  國家自然科學(xué)基金面上項(xiàng)目，2011.1－2011.12（主持）

　　若干多肽合成和化學(xué)修飾的新方法和關(guān)鍵技術(shù)及其在多肽藥物產(chǎn)業(yè)開發(fā)中的應(yīng)用  國家科技重大專項(xiàng) 2009.1-2010.12（參加）

　　青海沙蜥和紅尾沙蜥對高原低氧的適應(yīng)機(jī)制研究　國家自然科學(xué)基金面上項(xiàng)目，2013－2016（主持）

　　紅尾沙蜥適應(yīng)和耐受低溫的機(jī)制  國家自然科學(xué)基金面上項(xiàng)目，2015-2018（主持）

　　榮譽(yù)、獲獎(jiǎng)

　　蘭州大學(xué)第四屆“我最喜愛的十大教師”

　　蘭州大學(xué)2009年教書育人先進(jìn)個(gè)人

　　甘肅省高等學(xué)校實(shí)驗(yàn)室建設(shè)與管理先進(jìn)工作者 2006

　　甘肅省教學(xué)成果二等獎(jiǎng)  生物學(xué)實(shí)驗(yàn)技術(shù)隊(duì)伍建設(shè)與本科生創(chuàng)新能力培養(yǎng)模式及實(shí)踐 （排名第二） 2010

　　甘肅省教學(xué)成果二等獎(jiǎng)  生物學(xué)野外實(shí)習(xí)改革與實(shí)踐 （排名第二）2008

　　甘肅省自然科學(xué)二等獎(jiǎng) 我國石雞屬鳥類分類、生態(tài)和生態(tài)遺傳研究（排名第三） 2007

　　社會(huì)工作

　　中國生理學(xué)會(huì)比較生理學(xué)專業(yè)委員會(huì)副主任委員 2015－

　　中國生物化學(xué)與分子生物學(xué)會(huì)第十屆理事會(huì)理事 2010.8－2014.8

　　教育部高等學(xué)校生物科學(xué)與工程教學(xué)指導(dǎo)委員會(huì)委員2006-2010

　　中國動(dòng)物學(xué)會(huì)兩棲爬行動(dòng)物學(xué)分會(huì)理事

　　甘肅省生理學(xué)會(huì)副理事長

　　其它信息

　　教學(xué)工作

　　主講課程：動(dòng)物生理學(xué)、生命科學(xué)導(dǎo)論、人體解剖生理學(xué)

　　教育部雙語教學(xué)示范課程“動(dòng)物生理學(xué)”（負(fù)責(zé)人）

　　甘肅省精品課程“動(dòng)物生理學(xué)”（負(fù)責(zé)人）

　　甘肅省精品課程“生命科學(xué)導(dǎo)論”（負(fù)責(zé)人）

　　主持三項(xiàng)國家自然科學(xué)基金委“基礎(chǔ)科學(xué)人才培養(yǎng)基金”項(xiàng)目

　　編寫教材與著作

　　梅巖艾等主編 生理學(xué)原理 高等教育出版社 2011 （編者之一）

　　李仁德 董守良 陳強(qiáng) 人體及動(dòng)物生理學(xué)實(shí)驗(yàn)指導(dǎo) 蘭州大學(xué)出版社 2003

　　陳強(qiáng)  郭吉軍 沙漠與動(dòng)物 甘肅少兒出版社 1999

 

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