姓　　名： 袁若 性別： 男

出生年月： 1963-8-0 工作單位： 西南大學(xué)

所在院系： 化學(xué)化工學(xué)院 職稱： 教授

行政職務(wù)： 招生專業(yè)： 070302分析化學(xué)

研究領(lǐng)域： 分析化學(xué) 是否兼職： 否

指導(dǎo)博士生總數(shù)： 指導(dǎo)碩士生總數(shù)：

目前博士生數(shù)： 目前碩士生數(shù)：

個(gè)人簡(jiǎn)介

1984年獲湖南大學(xué)化學(xué)化工學(xué)院分析化學(xué)專業(yè)學(xué)士學(xué)位，1991年獲湖南大學(xué)化學(xué)化工學(xué)院分析化學(xué)專業(yè)碩士學(xué)位，1994年獲湖南大學(xué)化學(xué)化工學(xué)院分析化學(xué)專業(yè)博士學(xué)位。1994年分配在湖南大學(xué)分析測(cè)試中心工作，主要從事生物和化學(xué)傳感器的研究，1994年7月~1994年12月在香港浸會(huì)大學(xué)化學(xué)系做訪問(wèn)學(xué)者，從事基于主客體效應(yīng)的有機(jī)分子傳感器研究。1995年1月~1996年3月在日本大阪大學(xué)工學(xué)部應(yīng)用化學(xué)系米山宏（H.Yoneyama）教授實(shí)驗(yàn)室做博士后從事酶催化電化學(xué)氧化還原及納米材料傳感器研究。1998年8月~1999年8月在香港城市大學(xué)化學(xué)及生物系作高級(jí)研究員，從事電化學(xué)傳感器及DNA芯片研制工作。1999年調(diào)到西南大學(xué)化學(xué)化工學(xué)院工作。2001獲重慶市十大青年五四獎(jiǎng)?wù)拢?002年入選為重慶市首屆學(xué)術(shù)技術(shù)帶頭人后備人選， 2002年獲教育部?jī)?yōu)秀青年教師資助計(jì)劃資助，2004年獲得國(guó)務(wù)院政府津貼。2005年榮獲重慶市高校中青年骨干教師稱號(hào)。 　　袁若及其研究小組對(duì)生物及化學(xué)傳感器進(jìn)行了系統(tǒng)的研究，并取得了顯著的成果，其研究水平達(dá)到國(guó)際先進(jìn)水平。在免疫生物傳感器研究方面，他結(jié)合納米技術(shù)、反電荷技術(shù)、溶膠-凝膠技術(shù)研制出了白喉、乙肝、風(fēng)疹、腦膜炎等傳染性疾病及甲胎蛋白、癌胚抗原腫瘤標(biāo)志物生物傳感器并用于臨床試驗(yàn)。在酶生物傳感器研究方面，他采用生物膜技術(shù)、自組裝技術(shù)進(jìn)行生物電化學(xué)直接催化研制出葡萄糖氧化酶、過(guò)氧化氫酶、醇脫氫酶等生物酶?jìng)鞲衅?。在DNA生物傳感器研究方面，他采用交流阻抗技術(shù)、電容技術(shù)及芯片技術(shù)研究出了HIV基因片段檢測(cè)傳感器及地中海貧血、白血病等生物芯片。在生物催化合成研究方面，他采用金屬配合物、輔酶及電子媒體存在下借助生物酶催化電化學(xué)合成十余種對(duì)稱、非對(duì)稱羰基化合物、α-羥基氨基酸；建立起單酶催化手性羰基化合物的非對(duì)稱合成新體系，所得對(duì)映體過(guò)剩率（ee%）可達(dá)99-100%。在電化學(xué)傳感器研究方面，他定向設(shè)計(jì)合成了30余種新型手性、非手性Schiff堿金屬配合物及冠醚、杯環(huán)芳烴，采用主—客體分子識(shí)別技術(shù)及離子—載體特殊作用，研制出了20余種新型無(wú)機(jī)離子、有機(jī)分子化學(xué)傳感器。研制出的新型生物及化學(xué)傳感器已用于工業(yè)過(guò)程控制、臨床醫(yī)學(xué)及制藥工業(yè)。袁若及其研究小組研究的新型高分子膜pH電極，克服了目前玻璃膜pH 電極存在的高阻抗、易破碎、不耐HF腐蝕等缺陷，其研究成果已達(dá)到國(guó)際領(lǐng)先水平。該高分子膜pH傳感器產(chǎn)品于2003年被列為國(guó)家重點(diǎn)新產(chǎn)品計(jì)劃，并獲國(guó)家科技部科技型中小企業(yè)技術(shù)創(chuàng)新基金資助。2003年，他成立了一家重慶亞通化工有限公司，該公司已被列為重慶市高科技企業(yè)，其pH傳感器產(chǎn)品已走向市場(chǎng)受到用戶好評(píng)，并獲得較好的經(jīng)濟(jì)和社會(huì)效益。

著作及論文

在國(guó)內(nèi)外重要期刊上如《Anal. Chem.》、《J. Org. Chem.》、《Langmuir》、《Biosens. Bioelectron.》、《Electrochem. Commun.》、《Anal. Chim. Acta》、《Anal. Bioanal. Chem.》、《Electroanalysis》、《中國(guó)科學(xué)（B輯）》、《科學(xué)通報(bào)》《化學(xué)學(xué)報(bào)》等發(fā)表120余篇學(xué)術(shù)論文，其中80篇論文被SCI收錄。在《SCI》收錄中被他人引用315次，其中有三篇論文在《SCI》收錄中被他人引用次數(shù)超過(guò)30次。申請(qǐng)國(guó)家發(fā)明專利2項(xiàng)。 　　1. D. P. Tang, R. Yuan*, Y. Q. Chai, “Magnetic Control of an Electrochemical Microfluidic Device with an Arrayed Immunosensor for Simultaneous Multiple 1. D. P. Tang, R. Yuan*, Y. Q. Chai, “Magnetic Control of an Electrochemical Microfluidic Device with an Arrayed Immunosensor for Simultaneous Multiple Immunoassays,” Clinical Chemistry,2007, 53(7), 1323–1329. 　　2. D. P. Tang, R. Yuan*, Y. Q. Chai, et al, “Core/shell magnetic CoFe2O4/SiO2 porous composite nanoparticles as immobilized affinity supports for clinial immunoassays”, Advanced Functional? Material, 2007, 17(6): 976-982. 　　3. Y. Zhuo, R. Yuan*, Y. Q. Chai, A. L. Sun, Y. Zhang，J. Z. Yang, “A tris(2,2\'-bipyridyl)cobalt(III)-bovine serum albumin composite membrane for biosensors”, Biomaterials, 2006, 27, 5420-5429. 　　4. D. P. Tang, R. Yuan*, Y. Q. Chai, “Magnetic core-shell Fe3O4@Ag nanoparticle-coated carbon paste interface for studies of carcinoembryonic antigen in clinical immunoassay”, Journal of Physical Chemistry B, 2006, 110, 11640-11646. 　　5. N. Li, R. Yuan*, Y. Q. Chai, S. H. Chen, H. Z. An, W. J. Li, “ New Antibody Immobilization Strategy Based on Gold Nanoparticles and Azure I/Multi-Walled Carbon Nanotubes Composite Membrane for Amperometric Enzyme Immunosensor”, Journal of Physical Chemistry C,2007, 111, 8443-8450. 　　6. R. Yuan*, D. P. Tang, Y. Q. Chai, X. Zhong, Y. Liu, J. Y. Dai, “Ultrasensitive Potentiometric Immunosensor Based on SA and OCA Techniques for Immobilization of HBsAb with Colloidal Au and Polyvinyl Butyral as Matrixes”, Langmuir, 2004, 20(17), 7240 – 7245. 　　7. S. H. Chen, R. Yuan*, Y. Q. Chai, L. Y. Zhang, N. Wang, X. L. Li, “Amperometric third-generation hydrogen peroxide biosensor based on the immobilization of hemoglobin on multiwall carbon nanotubes and gold colloidal nanoparticles”, Biosensors and Bioelectronics, 2007, 22, 1268-1274. 　　8. D. P. Tang, R. Yuan*, Y. Q. Chai, “Biochemical and immunochemical characterization of the antigen-antibody reaction on a non-toxic biomimetic interface immobilized red blood cells of crucian carp and gold nanoparticles”, Biosensors and Bioelectronics, 2007, 22, 1116-1120. 　　9. D. P. Tang, R. Yuan*, Y. Q. Chai, Y. Z. Fu, J. Y. Dai, Y. Liu, X. Zhong, “New amperometric and potentiometric immunosensors based on gold noparticles/tris(2,2’-bipyridy) cobalt(III) multilayer films for hepatitis B surface antigen determinations”, Biosensors and Bioelectronics, 2005, 21(4), 539-548. 　　10. D. P. Tang, R. Yuan*, Y. Q. Chai, Y. Z. Fu, “Study on electrochemical behavior of a diphtheria immunosensor based on silica/silver/gold nanoparticles and polyvinyl butyral as matrices”, Electrochemistry Communications, 2005, 7(2), 177-182. 　　11. Y. Zhuo, R. Yuan*, Y. Q. Chai, D. P. Tang, L. Y. Zhang, N. Wang, X. L. Li, Q. Zhu,“A reagentless amperometric immunosensor based on gold nanoparticles/ thionine /Nafion-membrane-modified gold electrode for determination of α-1-fetoprotein”, Electrochemistry Communications, 2005, 7(4), 355-360. 　　12. L. Y. Zhang, R. Yuan*, X. Q. Huang, Y. Q. Chai, S. R. Cao, “Potentiometric immunosensor based on antiserum of Japanese B encephalitis immobilized in nano-Au/polymerized o-phenylenediamine film”, Electrochemistry Communications, 2004, 6(12),? 1222-1226. 　　13. R. Yuan*, L. Y. Zhang, Q. F. Li, Y. Q. Chai, S. R. Cao,“A label-free amperometric immunosenor based on the multi-layer structure of prussian blue / polymerized o-phenylenediamine / nano-Au /polymerized o-phenylenediamine / nano-Au / antibody for the determination of Japanese B encephalitis vaccine”, Analytica Chimica Acta, 2005, 531(1), 1-5. 　　14. Y. Zhuo, R. Yuan* , Y. Q. Chai, Y. Zhang, X. L. Li, Q. Zhu, N. Wang, “An amperometric immunosensor based on immobilization of hepatitis B surface antibody on gold electrode modified gold nanoparticles and horseradish peroxidase”, Analytica Chimica Acta, 2005, 548, 205-210. 　　15. D. P. Tang, R. Yuan*, Y. Q. Chai, “Electrochemical immuno-bioanalysis for carcinoma antigen 125 based on thionine and gold nanoparticles-modified carbon paste interface ”, Analytica Chimica Acta, 2006,? 564(2), 158-165. 　　16. L. Y. Zhang, R. Yuan, Y. Q. Chai, X. L. Li, “Investigation of the electrochemical and electrocatalytic behavior of positively charged gold nanoparticle and l-cysteine film on an Au electrode”, Analytica Chimica Acta, 2007, 59 (1),? 99-105. 　　17. Z. Q Tong, R. Yuan, Y. Q. Chai, Y. Xie, S. H. Chen, “A novel and simple biomolecules immobilization method: Electro-deposition ZrO2 doped with HRP for fabrication of hydrogen peroxide biosensor”, Journal of Biotechnology, 2007, 128, 567-575. 　　18. Y. T. Shi, R. Yuan*, Y.Q. Chai, M.Y. Tang, X. L. He, “Amplification of antigen–antibody interactions via back-filling of HRP on the layer-by-layer self-assembling of thionine and gold nanoparticles films on Titania nanoparticles/gold nanoparticles-coated Au electrode”, Journal of Electroanalytical Chemistry, 2007, 604, 9–16 　　19. Y. R. Yuan, R. Yuan*, Y. Q. Chai, Y. Zhuo, Y. T Shi, X. L. He, X. M. Miao, “A Reagentless Amperometric Immunosensor for Alpha-Fetoprotein Based on Gold Nanoparticles/TiO2 Colloids/Prussian Blue Modified Platinum Electrode”, Electroanalysis ,2007,19(13), 1402 – 1410. 　　20. F. C. Wang, R. Yuan, Y. Q. Chai, D. P. Tang, “Probing traces of hydrogen peroxide by use of a biosensor based on mediator-free DNA and horseradish peroxidase immobilized on silver nanoparticles”,Analytical Bioanalytical Chemistry, 2007, 387(2), 709-717. 　　21. Y. T. Shi, R. Yuan*, Y. Q. Chai, X. L. He, “Development of an amperometric immunosensor based on TiO2 Nanoparticles and gold Nanoparticles” , Electrochimica Acta, 2007, 52, 3518-3524. 　　22. H. Z. An, R. Yuan*, Y. Q. Chai, D. P. Tang, N. Li, “Dual-Amplification of Antigen-Antibody Interactions via Back-Filling Gold Nanoparticles on (3-Mercaptopropyl) Trimethoxysilane Sol-Gel Functionalized Interface” , Electroanalysis, 2007, 19(4), 479-486. 　　23. F. X. Gao, R. Yuan*, Y. Q. Chai, M. Y. Tang, S. R. Cao, S. H. Chen, “Amperometric third-generation hydrogen peroxide biosensor based on immobilization of Hb on gold nanoparticles /cysteine/ poly (p- aminobenzene sulfonic acid)-modified platinum disk electrode”, Colloids and Surfaces A:? 2007, 295, 223-227. 　　24. F. X. Gao, R. Yuan*, Y. Q. Chai, S. H. Chen, S. R. Cao, M. Y.Tang , “Amperometric Hydrogen Peroxide Biosensor Based on the Immobilization of HRP on nano-Au/Thi /Poly (p-Aminobenzene Sulfonic Acid)-Modified Glassy Carbon Electrode”， Journal of Biochemical and Biophysical Methods，2007, 70(3), 407-413. 　　25. G. R. Ye, Y. Q. Chai, R. Yuan, L. Zhou, Y. Li, L. N. Zhang, “Salicylate Ion-Selective Electrode Based on New Tetranuclear Copper Complexes of O-Vannlin-methionine as Neutral Carriers”,Analytical Sciences, 2007, 23(2), 171-176. 　　26. D. P. Tang, R. Yuan*, Y. Q. Chai, “Magnetic Control of an Electrochemical Microfluidic Device with an Arrayed Immunosensor for Simultaneous Multiple Immunoassays,” Clinical Chemistry,2007, 53(7), 1323–1329. 　　27. X. H. He, R. Yuan*, Y. Q. Chai, Y. Zhang, Y. T. Shi, “A new antibody immobilization strategy based on electrodeposition of gold nanoparticle and prussian blue for label-free amperometric immunosensor”, Biotechnology Letters, 2007, (1), 149-155. 　　28. Z. Q Tong, R. Yuan*, Y. Q. Chai, S. H. Chen, Y. Xie, “Direct electrochemistry of horseradish peroxidase immobilized on DNA/electro-deposited zirconium dioxide modified, gold disk electrode”, Biotechnology Letter, 2007, 29,791-795. 　　29. E. P. Luo, Y. Q. Chai, R. Yuan*, “Unsymmetrical tetradentate Schiff bases copper(II) complex as neutral carrier for thiocyanate-selective electrode”, Analytical Letters, 2007, 40, 369-386. 　　30. S. R. Cao, R. Yuan*, Y. Q. Chai, L. Y. Zhang, X. L. Li, F. X.Gao, “A mediator-free amperometric hydrogen peroxide biosensor based on HRP immobilized on a nano- Au/ poly 2,6-pyridinediamine- coated electrode”, Bioprocess and biosystems engineering, 2007, 30, 71-78. 　　31. F. C. Wang, R. Yuan*, Y. Q. Chai, “A new amperometric biosensor for hydrogen peroxide determination based on HRP-Nanogold-PTH-Nanogold-modified carbon paste electrode” , European food research and technology, 2007, 225(1), 95-104. 　　32. L. H. Gan, R. Yuan, “Influence of Cluster Size on the Structures and Stability of Trimetallic Nitride Fullerenes M3N@C80”, Chemphyschem, 2006, 7, 1306-1310. 　　33. D. P. Tang, R. Yuan*, Y. Q. Chai, “Electro-Transfer mediator microbiosensor Fabrication Based on Immobilizing HRP-Labeled Au Colloide on Gold Electrode Surface by 11-Mercaptoundecanoic noic Acid Monolayer”, Electroanalysis, 2006, 18(3) , 259-266. 　　34. S. H. Chen, R. Yuan*, Y. Q. Chai, L. Xu , N. Wang, X. L Li, L. Y. Zhang, “Amperometric hydrogen peroxide biosensor based on the immobilization of horseradish peroxidase (HRP) on the layer-by-layer assembly films of gold colloidal nanoparticles and toluidine blue”, Electroanalysis, 2006, 18(5) , 471-477. 　　35. Y. Zhuo, R. Yuan*, Y. Q. Chai, Y. Zhang, X. L. Li, N. Wang, Q. Zhu, “Amperometric enzyme immunosensors based on layer-by-layer assembly of gold nanoparticles and thionine on Nafion modified electrode surface for α-1-fetoprotein determinations”, Sensors and Actuators B, 2006, 114, 631-639. 　　36. Y. Liu, R. Yuan*, Y. Q. Chai, D. P.? Tang, J. Y. Dai , X. Zhong, “Direct electrochemistry of horseradish peroxidase immobilized on gold colloid/cysteine/nafion-modified platinum disk electrode” ,Sensors and Actuators B: Chemical,2006, 115, 109-115. 　　37. Q. Zhu, R. Yuan*, Y. Q. Chai, N. Wang, Y. Zhuo, Y. Zhang, X. L. Li, “A new potentiometric immunosensor for determination of α-fetoprotein based on improved gelatin–silver complex film”, Electrochimica Acta,2006, 51( 18), 3763-3768. 　　38. X. L. Li, R. Yuan*, Y. Q. Chai, L. Y. Zhang, Y. Zhuo，Y. Zhang, “Amperometric immunosensor based on toluidine blue/nano-Au through electrostatic interaction for determination of carcinoembryonic antigen”, Journal of Biotechnology, 2006, 123(3) 356-366. 　　39. S. R. Cao, R. Yuan, Y. Q. Chai, L. Y. Zhang,? X. L. Li,R. Chai,“Electrocatalytic Oxidation of Ascorbic Acid on 2,6-pyridinediamine / nano-Au / poly 2,6-pyridinediamine Modified Glassy Carbon Electrode and Its Analytical Application” Journal of the electrochemical society, 2006, 153(12), H223-H227. 　　40. Y. Z. Fu, R. Yuan, Y. Q. Chai, Y. Zhang, Y. G. Peng, “Electrochemical Immunoanalysis for Carcinoembryonic Antigen Based on Multilayer Architectures of Gold Nanoparticles and Polycation Biomimetic Interface on Glassy Carbon Eletrode”, Electroanalysis, 2006, 18(24), 2451-2457. 　　41. W. J. Xu, Y. Q. Chai, R.Yuan*. S. L. Liu “A novel thiocyanate-selective electrode based on a Zinc- phthalcyanine complex”, Analytical and Bioanalytical Chemistry，2006, 385: 926-936. 　　42. F. C. Wang, R. Yuan, Y. Q. Chai, “Direct electrochemical immunoassay based on a silica nanoparticles/sol–gel composite architecture for encapsulation of immunoconjugate”, Applied Microbiology and Biotechnology, 2006, 72(4), 671-675. 　　43. L. Y. Zhang, R. Yuan*, Y. Q. Chai, S. H. Chen, N. Wang, Q. Zhu,“Layer-by-layer self-assembly of films of nano-Au and Co(bpy)33+ for the determination of Japanese B encephalitis vaccine” , Biochemical Engineering Journal, 2006, 28(3),231-236. 　　44. D. P. Tang, R. Yuan*, Y. Q. Chai, X. Zhong, Y. Liu, J. D. Dai “Electrochemical detection of hepatitis B surface antigen using colloidal gold nanoparticles modified by a sol-gel network interface”, Clinical Biochemistry, 2006, 39(3), 309-314. 　　45. D. P. Tang, R. Yuan*, Y. Q. Chai, “Direct electrochemical immunoassay based on immobilization of protein-magnetic nanoparticle composites on to magnetic electrode surfaces by sterically enhanced?? magnetic field force”, Biotechnology Letters , 2006, 28(8), 559-565. 　　46. D. P. Tang, R. Yuan*, Y. Q. Chai, “Novel immunoassay for carcinoembryonic antigen based on protein A-conjugated immunosensor chip by surface plasmon resonance and cyclic voltammetry”, Bioprocess and Biosystem Engineering, 2006, 28, 315-321. 　　47. G. R. Ye, Y. Q. Chai, R. Yuan*, J. Y. Dai, “A mercury(II) ion–selective electrode based on N,N-dimethylformamide-salicylacylhydrazone as a neutral carrier”,Analytical Sciences, 2006, 22(4), 579-582. 　　48. D. P.? Tang, R. Yuan*, Y. Q. Chai, “ Ligand-Functionalized Core/Shell Ag@Au Nanoparticles Label-Free Amperometric Immun-Biosensor”, Biotechnology and Bioengineering, 2006, 94(5), 996-1004. 　　49. D. P. Tang, R. Yuan*, Y. Q. Chai, “. Electrochemical immunosensing strategies based on immobilization of anti-IgG on mixed self-assembly monolayers carrying surface amide or carboxyl groups”, Analytical Letters,2006, 39(9), 1809-1821. 　　50. Y. Z. Fu, R. Yuan*, Y. Q. Chai, L. Zhou, Y. Zhang, “Coupling of a Reagentless Electrochemical DNA Biosensor with Conducting Polymer Film and nanocomposite as Matrices for the Detection of the HIV DNA Sequences”, Analytical Letters, 2006, 39(3), 467 – 482. 　　51. Q. Zhu, R. Yuan*, Y. Q. Chai, Y. Zhuo, Y. Zhang, X. L. Li, N. Wang, “A Novel Amerometric Biosensor for Determination of Hydrogen Peroxide Based on Nafion and Polythionine as well as Gold Nanoparticles and Gelatin as Matrixes”, Analytical Letters, 2006, 39(3), 483 – 494. 　　52. W. J. Xu, Y. Q. Chai, R. Yuan, L. Xu, S. L. Lliu, “Highly Selective Iodide Electrode Based on the Copper(II)-N,N’-bis (salicylidene)-1,2-bis(p-aminophenoxy)-ethane Tetradentate Complex”, Analytical Sciences, 2006, 22, 1345-1349. 　　53. M. Y. Tang, R. Yuan, Y. Q. Chai, “A new amperometric biosensor based on HRP/nano-Au/L-Cysteine/ Poly (o-aminobenzoic acid)-membrane-modified platinum electrode for the determination of hydrogen peroxide”, Chinese Journal of Chemistry, 2006, 24, 1575-1580. 　　54. Y. Z. Fu, R. Yuan*, Y. Q. Chai, “Reagentless immunosensing assay via electrochemical impedance for hepatitis B surface antigen monitoring based on polypyrrole and gold nanoparticles as matrices”, Chinese Journal of Chemistry, 2006, 24, 59-64. 　　55 . A. L. Sun, Y. Q. Chai, R. Yuan, G. F. Gui, “AHighly Selective Salicylate Membrane Electrode Based on N, N’-(aminoethyl) ethylenediamide Bis–(2-salicylideneimine) Binuclear Copper(II) Complex as Neutral Carrier”, Chinese Journal of Chemistry, 2006, 24(7), 894-898. 　　56. N. Wang, R. Yuan,* Y. Q. Chai, D. P. Tang, Q. Zhu, X. L. Li, “Electrocatalytic oxidation of NADH based on self-assembled colloidal gold and Nafion matrixes and Co complex mediator”, Chinese Chemical Letters, 2006, 17(5), 683-686. 　　57. F. C. Wang, Y. Q. Chai, R. Yuan*, “A Novel Tetraiodocadmate (II) – PVC Membrane Electrode for the Potentiometric Determination of Cadmium (II)”, Chinese Chemical Letters, 2006, 17, 941-944. 　　58. D. P. Tang, R. Yuan* , Y. Q. Chai, L. Y. Zhang, X. Zhong, Y. Liu, J. Y. Dai, “Preparation and application on a kind of immobilization method of anti-diphtheria for potentiometric immunosensor modified colloidal Au and polyvinyl butyral as matrixes”, Sensors and Actuators B: Chemical, 2005, 104 ,199-206. 　　59．X. Zhong R. Yuan*, Y. Q. Chai, Y. Liu, J. Y. Dai and D. P. Tang “Glucose biosensor based on self-assembled gold nanoparticles and double-layer 2d-network 3-mercaptopropyl)- trimethoxysilane polymer onto gold substrate”，Sensors & Actuators: B. Chemical ，2005, 104 ,191-198 　　60．D. P. Tang, R. Yuan*, Y. Q. Chai, Y. Liu, J. Y. Dai, X. Zhong, “Novel potentiometric immunosensor for determination of diphtheria antigen based on compound nanoparticles and bilayer two-dimensional sol-gel as matrices”, Analytical and Bioanalytical Chemistry，2005, 381, 674-680. 　　61. R. Yuan*, Y. Liu, Q. F. Li, Y. Q. Chai, C. L. Mo, X. Zhong , D. P., Tang, J. Y. Dai, “Electrochemical characteristics of a platinum electrode modified with a matrix of polyvinyl butyral and colloidal Ag containing immobilized horseradish peroxidase” Analytical and Bioanalytical Chemistry，2005 , 381: 762-768. 　　62. L. Xu, R. Yuan*, Y. Q. Chai, X. L. Wang, “A Novel salicylate-selective electrode based on a Sn(IV) complex of salicylal-imino acid Schiff base”, Analytical and Bioanalytical Chemistry，2005, 381: 781–787. 　　63.L. Y. Zhang, R. Yuan*, X. Q. Huang, Y. Q. Chai, D. P. Tang, S. R. Cao, “A new label-free amperometric immunosenor for rubella vaccine”, Analytical and Bioanalytical Chemistry，2005 , 381(5), 1036-1040. 　　64. L. Xu, R. Yuan*,Y. Q. Chai, Y. Z. Fu，“Novel Membrane Potentiometric Thiocyanate Sensor Based on Tribenzyltin(IV) Dithiocarbamate”, Electroanalysis, 2005, 17(11), 1003-1007. 　　65. J. Y. Dai, Y. Q. Chai, R. Yuan*, Y. S. Zhang, Y. Liu, X. Zhang, D. P, Tang, “Thiocyanate-selective PVC membrane electrode based on tricoordinate Schiff base copper(II) complex”, Chemistry Letters, 2005, 34(1), 62-63. 　　66. L. Xu, R. Yuan*, Y. Q. Chai, “Mercury(II) ion Potentiometric Sensor Based on a Sulfur Schiff’s Base 1-(2-Hydroxy-1,2-diphenylethylidene)thiosemicarbazide as Ionophore” Chemistry Letters, 2005 , 34(3) , 440-441. 　　67. Q. Zhu, Y. Q. Chai, R. Yuan*, N. Wang , X. L. Li “Development of a Biosensor for the Detection of Carcinoembryonic Antigen Using Faradic Impedance Spectroscopy”, Chemistry Letters, 2005, 34(12), 1682-1684. 　　68. Y. Z.? Fu, R. Yuan*, L. Xu, Y. Q. Chai, Y. Liu, D. P. Tang, Y. Zhang. “Electrochemical impedance behavior of DNA biosensor based on colloidal Ag and bilayer two-dimensional sol-gel as matrices”, Journal of Biochemical and Biophysical Methods, 2005, 62(2), 163-174. 　　69. Y. Z. Fu, R. Yuan*，L. Xu, Y. Q. Chai, Y. Liu, X. Zhong, D. P. Tang, “Indicator free DNA Hybridization detection via EIS based on???? self-assembled gold nanoparticles and bilayer two-dimensional 3-mercaptopropyltrimeth- oxysilane onto a gold substrate” ,Biochemical Engineering Journal, 2005, 23(1) , 37-44. 　　70. J. Y. Dai, Y. Q. Chai,? R. Yuan*, L. X. An, Y. Liu, X. Zhong, D. P. Tang, “Tricoordinate schiff base copper (II) complex as neutral carrier for highly selective thiocyanate electrode”, Analytical Letters, 2005, 38(3), 389-400. 　　71. L. Xu, R. Yuan*, Y. Z. Fu, Y. Q. Chai, “Potentiometric membrane electrode for salicylate based on an organotin complex with a salicylal Schiff base of amino acid”, Analytical Sciences, 2005, 21(3), 287-292. 　　72. X. Zhong, R. Yuan*, Y. Q. Chai, J. Y. Dai，Y. Liu，D. P. Tang， “An Amperometric biosensor for glucose based on self-assembling nanoparticles and electrosynthesis of poly-o-diaminobenzene on the Prussian blue modified gold electrode”, Analytical Letters， 2005 ,38(7)，1085-1097. 　　73. F. C. Wang， Y. Q. Chai, R. Yuan*, C. H. Chen, J. Y. Dai, L. Xu,“A Selective Membrane Electrode for Thiocyanate Ion Based on a Bis-taurine-salicylic Binuclear Copper(II) Complex as Ionophore”，Chinese Journal of Chemistry, 2005, 23(7), 865-869. 　　74. D. P. Tang, R. Yuan*, Y. Q. Chai, L. Y. Zhang, J. Y. Dai, Y. Liu, X. Zhong, “Potentiometric Immunosensor Based on Immobilization of Hepatitis B Surface Antibody on Platinum Electrode Modified Silver Colloids and Polyvinyl Butyral as Matrixes”, Electroanalysis, 2005, 17(2), 155-161. 　　75. L. Y. Zhang, R. Yuan*, Y. Q. Chai, X. L. Li, X. Zhong, “An amperometric immunosensor for rubella vaccine”, Analytical Letters, 2005, 38(10), 1549-1558. 　　76. J. Y. Dai, R. Yuan*, Y. Q. Chai, L. X. An, X. Zhong, Y. Liu, D. P. Tang, “Highly thiocyanate- selective pvc membrane electrode based on lipophilic ferrocene derivative”, Electroanalysis, 2005, 17(20), 1865-1869. 　　77. Y. Q. Chai, J. Y. Dai, R. Yuan*, X. Zhong. Y. Liu, D. P. Tang, “Highly thiocyanate-selective membrane electrodes based on the N,NN-bis-(benzaldehyde)-glycine copper(II) complex as a neutral carrier”, Desalination, 2005, 180, 207-215 　　78. Y. Z. Fu, R. Yuan*, D. P. Tang, Y. Q. Chai, “Study on the immobilization of anti-IgG on Au-colloid modified gold electrode via potentiometric immunosensor, cyclic voltammetry, and electrochemical impedance techniques”, Colloids and Surfaces B: , 2005, 40(1), 61-66. 　　79．Y. Q. Chai, R. Yuan*, J. Y. Dai , L. Xu, A. L. Sun, G. F. Gui, “Highly salicylate-selective membrane electrode based on? N,N’-bis-(furaldehyde)-glycinecopper(II) complex as neutral carrier”, Analytical Letters, 2005, 38(1), 45-56 　　80. Y. Liu, R. Yuan*, Q. F. Li, Y. Q. Chai, X. Zhong, D. P. Tang,? J. Y. Dai, “A New Biosensor for Hydrogen Peroxide Based on Ag Colloid-modified Electrode and Azure C Mediation”, S. Afr. J. Chem., 2005, 58, 4–8. 　　81. D.P. Tang, R. Yuan, Y.Q. Chai, X. Zhong, Y. Liu, J.Y. Dai, L.Y. Zhang，“Novel potentiometric immunosensor for hepatitis B surface antigen using a gold nanoparticle-based biomolecular immobilization method”? Analytical Biochemistry, 2004, 333(2), 345-350. 　　82．D. P. Tang, R. Yuan,Y. Q. Chai, J. Y. Dai, X. Zhong, Y. Liu, “A novel immunosensor based on immobilization of hepatitis B surface antibody on platinum electrode modified colloidal gold and polyvinyl butyral as matrices via electrochemical impedance spectroscopy”, Bioeletrochemistry, 2004, 65(1),15-22. 　　83．Y. Q. Chai, R. Yuan, L. Xu, W. J. Xu, J. Y. Dai and F. Jiang, “A Highly sensitive PVC membrane iodide electrode based on the complexes of mercury(II) as neutral carrier”, Analytical and Bioanalytical Chemistry，2004 , 380(2), 333-338. 　　84．Z. Y. Sun, R. Yuan, Y. Q. Chai, L. Xu, , X. X. Gan, W. J. Xu，“Study of a bis-furaladehyde Schiff base copper(II) complex as carrier for preparation of highly selective thiocyanate electrodes”，Analytical and Bioanalytical Chemistry，2004, 378, 490~494. 　　85. D.P. Tang, R. Yuan, Y.Q. Chai, L. Y. Zhang, X. Zhong, J. Y. Dai, Y. Liu, “Novel potentiometry immunoassay with amplified sensitivity for diphtheria antigen based on nafion, colloidal Ag and polyvinyl butyral as matrixes”, Journal of Biochemical and Biophysical Methodes, 2004, 61,299-311. 　　86．D.P. Tang, R. Yuan, Y.Q. Chai, X. Zhong, Y. Liu, J. Y. Dai, “Novel potentiometry immunoassay for the detection of diphtheria antigen based on colloidal gold and polyvinyl butyral as matrixes”, Biochemical Engieering Journal, 2004, 22, 43-49. 　　87．X. Q. Huang, Y. Q.Chai, R. Yuan, X. L. Wang, Q. F. Li, “Highly selective thiocyanate electrode based on bis-[N-(2-hydroxyethyl)salicylaldimino]copper(II) complex as a neutral carrier”, Analytical Sciences, 2004, 20(8),1185-1188. 　　88. J. Y. Dai, Y. Q. Chai, R. Yuan, X. Zhong, Y. Liu, D. P. Tang, “Bis-dimethylaminobenzaldehyde Schiff-base Cobalt(II) Complex as a Neutral Carrier for a Highly Selective Iodide Electrode”, Analytical Sciences, 2004, 20(12), 1661- 1666. 　　89. 周路，葉光榮，袁若*，柴雅琴，陳素明，“甲磺酸帕珠沙星分子印跡手性電容型傳感器”，中國(guó)科學(xué)，B輯：2007, 37(1), 48-53. 　　90. 袁若*，曹淑瑞，柴雅琴，高鳳仙，趙青，唐明宇，童忠強(qiáng)，謝軼，“血紅蛋白/帶正電的納米金層層自組裝膜修飾電極的制備及其電催化性能的研究”，中國(guó)科學(xué)，B輯： 2007, 37(2), 170-177. 　　91. 張麗娜，柴雅琴，袁若*，李艷，葉光榮，“基于2,3-丁二酮雙縮氨基硫脲為中性載體的新型銀離子選擇性電極的研究”化學(xué)學(xué)報(bào)，2007, 65(6), 537-541. 　　92. 袁若*, 卓穎, 柴雅琴, 張英, 孫愛(ài)麗，“基于納米金/硫堇層層自組裝的新型電流型酶-癌胚抗原免疫傳感器”，中國(guó)科學(xué) B(輯)，2006, 36(5), 425-432. 　　93. 袁若*，唐點(diǎn)平，柴雅琴，張凌燕，劉顏，鐘霞，戴建遠(yuǎn)，“高靈敏電位型免疫傳感器對(duì)乙型肝炎表面抗原的診斷技術(shù)研究”，中國(guó)科學(xué) (B 輯), 2004, 34(4), 279-286. 　　94. 黎雪蓮, 袁若*, 柴雅琴, 朱強(qiáng), 張凌燕, 王娜，“基于多層酶/納米金固定甲胎蛋白免疫傳感器的研究”，化學(xué)學(xué)報(bào)，2006, 64(4), 325-330. 　　95. 張凌燕，袁若*，柴雅琴，曹淑瑞，黎雪蓮，王娜，“基于辣根過(guò)氧化物酶 / 納米金 / 辣根過(guò)氧化物酶 /多壁納米碳管修飾的過(guò)氧化氫傳感器的研究”，化學(xué)學(xué)報(bào)，2006, 64(16),1711-1715. 　　96. 歸國(guó)風(fēng), 柴雅琴, 袁若*，孫愛(ài)麗，王福昌，“新型雙核銅金屬配合物為中性載體的硫氰酸根離子高選擇性電極的研究”，化學(xué)學(xué)報(bào)，2006, 64(21),2185-2189. 　　97．唐點(diǎn)平，袁若*，柴雅琴，劉顏，鐘霞，戴建遠(yuǎn)，“納米金修飾玻碳電極固載抗體電位型白喉類毒素免疫傳感器的研究”化學(xué)學(xué)報(bào)，2004, 62(20): 2062-2066. 　　98．王秀玲，袁若*，徐嵐，柴雅琴，孫志勇，黃曉靖，李群芳，趙勤，“雙安息香縮三乙四胺雙核鈷硫氰酸根的離子電極研究”，高等學(xué)校化學(xué)學(xué)報(bào)，2004, 25(4), 633-635.

承擔(dān)項(xiàng)目

1994年以來(lái)，袁若作為項(xiàng)目負(fù)責(zé)人主持并完成了國(guó)家自然科學(xué)基金、科技部科技型中小企業(yè)創(chuàng)新基金、教育部?jī)?yōu)秀青年教師資助計(jì)劃基金、國(guó)家教育部留學(xué)生基金、重慶市科委攻關(guān)基金、重慶市自然科學(xué)基金等12項(xiàng)課題，并參加了日本文部省重點(diǎn)基金、香港RGC基金、國(guó)家自然科學(xué)重點(diǎn)基金、中國(guó)科學(xué)院長(zhǎng)春應(yīng)用化學(xué)研究所電化學(xué)開(kāi)放實(shí)驗(yàn)室基金課題、國(guó)家教委博士點(diǎn)基金等6項(xiàng)課題的研究。 　　主持的科研項(xiàng)目 　　1. 國(guó)家自然基金項(xiàng)目：三維網(wǎng)狀超分子納米水膠及金屬納米微粒固載抗體蛋白的高靈敏電化學(xué)免疫傳感器研究（2007-2009） 　　2. 重慶市自然科學(xué)基金：高靈敏納米金修飾白喉免疫生物傳感器研究(2004.8~2007.8) 　　3. 科技部科技型中小企業(yè)技術(shù)創(chuàng)新基金: 高分子膜pH傳感器(2003.8~2005.8) 　　4. 重慶市自然科學(xué)基金：酶催化高立體選擇性手性物電化學(xué)合成及其傳感器研究（2002.8~2005.8） 　　5. 教育部?jī)?yōu)秀青年教師資助計(jì)劃項(xiàng)目：?jiǎn)蚊复呋吡Ⅲw選擇性手性醇電化學(xué)合成及其傳感器研究（2002.1~2005.1） 　　6. 重慶市科委攻關(guān)項(xiàng)目：新型非玻璃膜固態(tài)pH傳感器研制（2000.6~2003.6） 　　7. 湖南省自然基金：高選擇性醇脫氫酶催化光學(xué)活性物電化學(xué)還原及生物傳感器研究（1999~2000） 　　8. 國(guó)家自然科學(xué)基金：?jiǎn)蚊复呋哌x擇性羰基手性物電化學(xué)還原及其傳感器研究（1998~2000） 　　9. 教育部留學(xué)生基金：酶催化電化學(xué)還原及其生物傳感器研究（1997~1999） 　　10. 湖南省自然基金：新型金屬配合物中性載體陽(yáng)離子選擇電極研究（1995~1996）